When doing a design for Exchange 2010 it is takes a lot of effort to look at all aspects of a system before choosing a product. Choosing the right size load balancer for exchange entails looking at the systems as a whole and how it will be used. A few of the things I look at before making a decision are
1. Client Count
2. Protocols used
3. Client connection speeds
4. Encryption Used
5. Device type
6. Message size
These numbers will tell a person a lot about Exchange and how it is being used so that one can make an educated decision about the size and capabilities of a load balancer. Unfortunately time constraints or a number of other factors do not always allow one the time to analyze and Exchange environment. In other cases a general idea is need for general discussion or budgetary estimates are needed prior to a deep analysis is done. Luckily Kemp Technologies has come up with a handy tool that can be used to get a broad look at what products they offer and a general idea of how to size them, given certain parameters. Take a look at the tool and give it a whirl.
http://www.kemptechnologies.com/fileadmin/templates/sizingDoc/lme_calc_2k/lme_calc_2k.htm

